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doi:10.1007/s00011-010-0238-9

For patients pursuing systemic regenerative or wound-healing protocols, injectables have a legitimate role under physician supervision, but if you are asking about wrinkles, skin firmness, or hair thinning, topical is the right delivery method

Practical decision framing in the research-use community: if the research interest is structural repair, soft-tissue work, or skin remodeling alone, GLOW covers those bases