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& Sumi, D

[PMC free article: PMC2270041] [PubMed: 10922269] 22

When neuronal mitochondrial dysfunction leads to decreased OXPHOS efficiency, astrocyte-derived lactate can enter neuronal mitochondria via MCT2, converting to pyruvate for participation in the TCA cycle, thereby generating ATP to maintain neuronal membrane potential and synaptic activity (195)

B6 (Pyridoxine): Can ease nausea in the first trimester and supports hormone metabolism

For each 1mL/min decrease in creatinine clearance, a 1 per cent increase in mortality was observed (McAlister FA et al, Circulation 2004)

Conversely, they induce the downstream signaling pathways involving protein kinases of the MAPK and phosphoinositide 3-kinase (PI3K) cascades [12]