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Iron death, characterized by oxidative stress due to intracellular Fe2+ accumulation, leading to large amounts of ROS production, ultimately results in cell death (161) and contributes to various cardiovascular diseases including atherosclerosis, I/R injury, HF, myocardial infarction and adriamycin cardiomyopathy (162)

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62 Peaks from the original manuscript (number of peaks = 336,500) were annotated to gene bodies and nearby (100 bp to +1000 bp) promoters (GENCODE hg38 version 104)