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Pre-existing oxidative stress creates a docking-ready conformation of the SARS-CoV-2 receptor-binding domain

This simplified the trial design but raises legitimate questions about whether weight-based dosing might improve outcomes

Vitamin D receptor activated by vitamin D administration alleviates Mycobacterium tuberculosis -induced bone destruction by inhibiting NFB-mediated aberrant osteoclastogenesis

Cryo-EM data were collected on a Tecnai Arctica (FEI, Hillsboro, OR) at 200 kV, utilizing an energy filter and a direct electron detector (Gatan, Pleasanton, CA) operated by EPU software (Thermo Fisher Scientific, Waltham, MA)

doi: 10.1186/s12879-020-05126-z 87 LiH

Moreover, an inefficient immune system may favour viral persistence (321), or reactivation of latent viruses, whereas an overreactive immune system may lead to an excessive inflammation (89)