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Lutein also affects the polarization of macrophages, favoring the M2 (anti-inflammatory) phenotype over the M1 (pro-inflammatory) phenotype, which lowers inflammation and promotes tissue repair [96]

10.1016/j.cca.2018.11.003 125

Longo and colleagues have synthesized a small molecule BDNF mimetic that activates the TrkB receptor and facilitates motor learning in traumatic brain injured rats [18]