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Despite the obvious consequences of the functional B2 deficiency in the metabolism of B12, the majority of authors do not seem cognizant of this (Obeid etal, 2015), and seem to believe that B12 deficiency only occurs due to low intake of the vitamin, rather than ineffective processing, and are unaware of the phenomenon of Paradoxical B12 deficiency

These are very effective at raising blood levels of vitamin B12, thus preventing or reversing a vitamin B12 deficiency

It is not typically a sign of a severe medical condition