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Ismail Hakki Kalkan and Murat Suher - The relationship between the level of glutathione, impairment of glucose metabolism and complications of diabetes mellitus - Pak J Med Sci - 2013 Jul-Aug

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IGF-1 LR3 has been used extensively in this context precisely because its extended half-life allows sustained receptor activation in cell culture and in vivo models without the impractical dosing frequency that native IGF-1 would require

In hepatocellular carcinoma (HCC), GLS2 inhibited proliferation in vitro and lung metastasis in a xenograft mouse model by inhibiting the small GTPase Rac1 13