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Fermented Wheat Germ Extract Fermented wheat germ extract (FWGE) is a natural product developed in Europe, where it is approved as a dietary food for special medical purposes in cancer patients. It is available in powder form, and has been the subject of numerous preclinical and clinical studies investigating its potential as both a direct chemotherapeutic agent as well as a complement to standard cancer radiotherapy and chemotherapy

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The largest trial involving DSIP to date, which included a total of 107 volunteers, reported that the peptide was generally well-tolerated with mostly minor side effects, which included [8]: Low blood pressure Increased sweating Headache Nausea Vertigo Considering that the drop in blood pressure was reported as moderate to severe in some patients, researchers should consider hypotension as a potentially exclusionary criterion for DSIP research