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and chow diet T.2918.4x5R sourced from Inotiv

FIGURE 2 Inhibition of Sat1 alleviates MIRI by regulating ferroptosis in vivo To further investigate the role of Sat1 in MIRI in vivo , AAV9 was applied in SD rats to suppress Sat1 expression

received funding from Paris Sciences et Lettres University/lUniversit Cte dAzur (PSL/OCAV)

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However, some studies have shown that excessive ferroptosis can lead to the release of damage-associated molecular patterns and the activation of immune responses triggered by ferroptotic damage, which promote tumor growth and metastasis

So, we decided the study design be based on the pre-post intervention model