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This means that the difference of GSH content in the CDDP-sensitive cells and the CDDP-resistant cells is mainly accounted for by the difference of GSH synthesis rate

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The Lapatinib-GPx4 complex showed a different behavior with slight fluctuation at the initial phase of the simulation at 5ns (310) for the ligand but stabilized within a fluctuation range of 1216 until the end of the simulation

Embodiment 186 The method according to any one of embodiments 172- said immunoconjugate or antibody is administered in a pharmaceutical composition comprising a pharmaceutical acceptable carrier