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Ann NY Acad Sci 1351 : 110

Both, mechanical load shifts and exposure of the NP to immune surveillance initiate biological reactions that are injury type specific

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The levels of several metabolites, such as amino acids, lipids, and carbohydrates, changed as a result of these alterations

whether synergistic effects reduce immunosuppressant doses or potential antagonism (e.g., immunosuppressants altering iron metabolism/ferroptosis) exists remains unknown