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In aging mammals, these rhythms tend to adapt to the age stage by modifying its period, phase, and amplitude until later life, when these rhythms fragment or dampen, contributing to metabolic dysfunction, cognitive decline, immunosenescence, and sleep disruption (Liu et al., 2024)

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The unnamed 72-year-old man went to the emergency room with inflamed red streaks all over his back and upper buttocks and said that the rash was so itchy and painful that he couldn't sleep, according to a medical case report published on October 12 in the New England Journal of Medicine

Vanle B, Olcott W, Jimenez J, Bashmi L, Danovitch I, IsHak WW