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This acquired, degenerative condition is characterized by drusen deposits that interfere with the retinal pigment epithelium (RPE) and Bruchs membrane, specifically affecting the macula, which is essential for central, detailed, and color vision [410]

Dirnagl, U., Iadecola, C

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Consequently, alternative PET tracers, such as radiolabeled amino acids (11C-methionine [11C-MET], 18 F-fluoroethyltyrosine [ 18 F-FET], and 18 F-fluoro-L-DOPA [ 18 F-FDOPA]), along with hypoxia agents such as 18 F-fluoromisonidazole ( 18 F-FMISO), have gained prominence for their ability to visualize gliomas independent of BBB integrity