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S., & Romanini, D

( g ) HyPerRed fluorescence in synchronized sorted MCF-7 cells were analyzed

No randomized controlled trial

In this state, it can no longer function as an antioxidant

The study established that FOXO4 maintains senescent cell viability by targeting p53 to the nucleus and preventing apoptosis, and that disrupting the FOXO4-p53 interaction with FOXO4-DRI causes p53 nuclear exclusion and cell-intrinsic apoptosis in ionising radiation-induced and doxorubicin-induced senescent IMR90 fibroblasts