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The ethanolic extract of BM at the dose of 200 mg/kg showed a good hepatoprotective effect in nitrobenzene-induced liver damage in mice model by an increase in SOD, CAT and GPx enzymes and by normalizing the serum marker enzymes such as aspartate transaminase, alanine transaminase, and alkaline phosphatase

This research has been conducted following the tenets of the Declaration of Helsinki and approved by the ethics committee of Medical Faculty

Stress is a critical player in CYP3A, CYP2C, and CYP2D regulation: role of adrenergic receptor signaling pathways

Similarly, nine of the seventeen residues (Q637 3.29 , H641 3.33 , H721 ex2 , S726 5.39 , F730 5.43 , W775 6.48 , F778 6.51 , L782 6.55 , and C801 7.39 ) mediate activation by cyclamate, while six (Q637 3.29 , H641 3.33 , W775 6.48 , F778 6.51 , L782 6.55 , and C801 7.39 ) influence receptor inhibition by lactisole as well as receptor activation by cyclamate [superscript refers to the nomenclature suggested for class C GPCRs by Pin et al