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M., Daz, J

GPX4 is a master regulator of ferroptosis by functioning as a lipid repair enzyme and detoxifying lipid hydroperoxides, utilizing GSH as an essential cofactor

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Notably, such treatments also raise internal spermidine levels in plants, presenting a promising avenue for enhancing human dietary intake through everyday food

Intercurrent illnesses or medication changes (including addition of sedating medications or unavailability of regular symptomatic AD medications): This estimand will be analysed in participants who undergo follow-up RBANS assessment at 180 days (+0, 10 days) and who have taken at least 80% of the study medication, and where there have been no intercurrent events blindly adjudicated as affecting cognition (principal stratum strategy) Secondary estimand epigenetic change 1

FOXO4-DRI: A Novel Therapy for Senescent Cell Elimination