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Database 2015:

We prioritized peer reviewed studies that provided mechanistic evidence and clear relevance to osteoarthritis cartilage repair, and excluded non peer reviewed reports or studies lacking mechanistic characterization

16 In 2019, two groups independently reported that the FSP1 (ferroptosis suppressor protein 1)-CoQ 10 (coenzyme Q 10 )-NAD(P)H pathway inhibits ferroptosis via a GPX4-independent mechanism