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Building on this framework, we evaluate emerging applications in major human diseases, including cancer, traumatic injury, cardiovascular disorders, neurodegenerative disorders, and inflammatory or immune-mediated conditions, with particular attention to neuroregeneration and systems-level repair

Oxidative stress-mediated senescence and death of RPE and subsequent death of photoreceptors have been observed in age-related macular degeneration (AMD)

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Meanwhile, for many years now, scientists have studied the effects of low-dose naltrexone (LDN) on the gut epithelial barrier in treatment-resistant Ulcerative colitis patients