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A ferroptosis inhibitor reduces carotid artery neointimal plaques and AS in C57BL/6J and ApoE / mice, indicating that suppressing ferroptosis in VSMCs may alleviate proliferative vascular disease (Yan et al., 2023)

To conclude, iron metabolism and lipid peroxidation contribute to the occurrence of ferroptosis, and eventually up-regulate inflammation

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194 KCNK6, a potassium channel protein, facilitates potassium efflux and promotes the activation of the NLRP3 inflammasome, contributing to inflammation and tumor progression

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