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Y-YF collected and provided the sample for this study

A mixed-effects model was used to determine whether the group and time group interaction were significant 45

Second, heterogeneity in study endpoints also contributes to inconsistent findings

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c , Top, volcano plot showing relative fold change (log 2 ) in ER-metabolite abundance versus log 10 (P value) from ER-tag HEK293T cells treated with antimycin compared to untreated