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For example, KRAS mutations are common in several types of cancer and are linked to the activation of the MAPK pathway, making them potential biomarkers for selecting patients for ERK1/2-targeted therapies (Hong et al., 2023[51])

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discovered a new compound, erastin, which had a selectively lethal effect on RAS-expressing cancer cells, but the manner of cell death was different from what had been seen before

However, taking L-glutamine alone is not always enough to significantly raise glutathione levels, especially if you are facing environmental stressors that deplete your antioxidant stores faster than your body can rebuild them

There are indications of effects on certain biomarkers, but results are context-dependent