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It was reported that the iron could convert intracellular reductive molecule GSH to GSSG to impair the oxidation resistance ability of cancer cells 28 , thus the GSH depletion and OH generation of peptide-porphyrin conjugates were assessed separately under H 2 O 2 treatment (Supplementary Fig

5 Rao J, Wang H, Ni M, Wang Z, Wang Z, Wei S, Liu M, Wang P, Qiu J, Zhang L, et al

Targeting Co-Regulatory Feedback Loop of MYC and GSPT1 By MYC/GSPT1 Dual Degradation Is Synthetic Lethal in Combination with Ven/Aza in TP53 Mutant Acute Myeloid Leukemia Stem and Progenitor Cells