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18 Support for the poorer bioavailability of cyano-B12 comes from a study comparing sublingual cyano- with methyl-B12 (both 1000 g per day), which found that both forms led to a normalisation of B12 status, but B12 levels increased significantly more in the methyl-B12 form compared with the cyano-B12 form, although the formulations also had other differences the former was a tablet, the latter a spray
While individual ingredients like L-carnitine, B12, and choline have been studied independently and show benefits, the specific MIC B12 combination used in lipotropic shots has not been evaluated in large-scale clinical trials
(PubMed) Cacciapuoti F

Beef liver, cooked, pan-fried (3 ounces) Amount in micrograms (mcg): 70.7 mcg Clams (without shells), cooked (3 ounces) Amount in micrograms (mcg): 17 mcg Oysters, eastern, wild, cooked (3 ounces) Amount in micrograms (mcg): 14.9 mcg Nutritional yeast, fortified Amount in micrograms (mcg): 8.324 mcg Salmon, Atlantic, cooked (3 ounces) Amount in micrograms (mcg): 2.6 mcg Tuna, light, canned in water (3 ounces) Amount in micrograms (mcg): 2.5 mcg Beef, ground, 85% lean meat (3 ounces) Amount in micrograms (mcg): 2.4 mcg 2% milk, 1 cup Amount in micrograms (mcg): 1.3 mcg Yogurt, plain, fat free (6 ounces) Amount in micrograms (mcg): 1 mcg Breakfast cereal fortified with 25% of daily value Amount in micrograms (mcg): 0.6 mcg Cheddar cheese (1.5 ounces) Amount in micrograms (mcg): 0.5 mcg 1 large egg, whole, cooked Amount in micrograms (mcg): 0.5 mcg Turkey, breast meat, roasted (3 ounces) Amount in micrograms (mcg): 0.3 mcg Vitamin B12 Overdose: Key Takeaways Vitamin B12 is a crucial nutrient that supports a variety of important bodily functions, including red blood cell formation, neurological health, and DNA synthesis

Researchers use it in laboratory studies of fat metabolism under controlled conditions