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PD rats were assigned randomly to five groups of six rats: 1) control group receiving no treatment (WT), 2) intranasal infusion of vehicle only (Sham), 3) mitochondria alone (Mito), 4) Pep-1-labelled mitochondria (P-Mito) and 5) Pep-1 alone (Pep-1)

PCA score plots displayed clear separation between buffer and serum datasets, as well as distinct clustering of DENV2 from other viruses, consistent with high specificity and limited cross-reactivity