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& Tang, J

These findings collectively highlight the immense therapeutic potential of marine-derived peptides, particularly in addressing complex inflammatory disorders

Mechanistically, the binding of BPC157 to FBXO22 induces steric hindrance that suppresses FBXO22-mediated ubiquitination and degradation of its substrate BACH1

Glutathione is a tri-peptide (L-g-glutamyl-L-cysteinyl-glycine) that acts as both reducing agent and capping agent, which assemble on the surface of AuNCs via a stable gold-thiol linkage (from cysteine) and imparts the nanoclusters with a net negative surface charge (zeta potential = 32 4.2 mV, pH = 7.5) due to the presence of terminal carboxylic acid functional groups (sketch depicting the assembly of glutathione molecules on GSH-AuNCs and the chemical structure of glutathione peptide is shown in Fig

However, these safety data come from systemic administration studies

While these effects demonstrate dopamine system modulation relevant to ADHD pathophysiology (the disorder involves dopamine dysregulation), amphetamine-induced stereotypy models psychosis and stimulant abuse, not ADHD symptoms