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In a study carried out by Asthana et al., zinc oxide nanoparticles showed significant binding affinity with -synuclein fibrils via a) enthalpy driven interaction with the amphipathic KA: TKE/QGV repeats and b) enthalpy-driven interaction with the central NAC region as well as the C terminus

Funding The author(s) declare that financial support was received for the research and/or publication of this article

doi: 10.1021/acs.est.5b05387 233 ZhouXKramerJPCalafatAMYeX

Receptor for advanced glycation end products (RAGE) is a key factor for plaque destabilization in diabetes mellitus, where its downregulation may suppress atherosclerotic plaque development, an effect mediated by NF-B inhibition (100, 101)

Specific inflammatory biomarkers for early detection of MASLD Chronic low-grade inflammation is a central feature in the pathogenesis of MASLD