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The metabolic pathways through which these molecules act to stimulate TAG hydrolysis and FA release have been studied extensively and reviewed in detail (6, 17, 18, 29, 63, 64, and references contained therein)

In addition to improve the metabolic function through directly exerting the anti-oxidative and anti-inflammatory effects, ALA also plays an important role in energy metabolism through its involvement in mitochondrial multi-enzyme complexes (19, 29)

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These high linear energy transfer (LET) particles are ionizing radiation capable of damaging cellular DNA, disrupting its replication process and ultimately causing cell death [96]

Researchers continue to investigate the signalling networks that regulate these processes, with 5-Amino-1MQ appearing in laboratory studies exploring the complex relationship between metabolism, enzyme function and cellular physiology