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Many users consider this a benefit rather than a side effect

High levels of glucocorticoids synergize with excitatory amino acids, such as glutamate, to exacerbate excitotoxic damage a process linked to impaired glucose uptake and reduced energy metabolism in neurons (133)

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However, changes in the redox state stabilize Nrf2, allowing it to enter the nucleus and regulate gene transcription related to oxidative stress (164)