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The fact that of all tested tissues, we identified T H 17 cells accumulating solely in Pps and dural meninges of 5xFAD mice, suggests that gut-educated CD4 + T cells may be a source of disease-associated IL-17A during AD, supporting a gut-brain axis in which T H 17 cells, induced in intestine-associated tissues, could drive neuroinflammation 76 and promote worsening of cognition 77

M., Huang, B., & Wu, P

F.FreitasA

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Negishi S, Miyao K, Ohara F, Motegi K, Wakabayashi H, Yokota H et al (2022) Feasibility of trimethoprim/sulfamethoxazole desensitization therapy in hematological diseases