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Among the other drug efflux ATPase genes previously reported to contribute to cisplatin resistance ABCG2, ABCC2, ABCA1 , and ABCC1 were significantly up-regulated in at least one cell line (Figure S3cf), while ATP7B was unchanged after exposure to e-cigarette aerosol extract (Figure S3g)

Knoepfler has long argued for a temporary moratorium on heritable human gene editing until ethical guidelines can be established