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At the same time, the phosphorylation of Ser727 and the acetylation of Lys685 of STAT3 were enhanced, and the phosphorylation of AKT was also significantly increased

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The NF-B inducing kinase (NIK) phosphorylates and activates IK, then synergistically regulating the phosphorylation of p100 (Senftleben et al., 2001

Graphical Abstract Keywords Drug hepatotoxicity, Acetaminophen, Lipid peroxidation, Oxidative stress, Ferroptosis, Glutathione peroxidase 4, Erastin, Ferrostatin-1, Methotrexate, Rifampicin, Isoniazid, Natural products Introduction Drug-induced liver injury (DILI) is a significant clinical problem worldwide

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Key Characteristics Composition : Bacteriostatic Sodium Chloride typically contains 0.9% sodium chloride and 0.9% benzyl alcohol per ml as a preservative