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In dementia patients, neurotransmitter release is typically abnormal (Teleanu et al., 2022

3 The blood supply comes from three main sources: the inferior-lateral genicular artery, an anastomotic arch between the inferior medial genicular artery and anterior tibial recurrent artery, and retropatellar from Hoffa fat pad

The advent of vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs) has extended median OS to 2430 months, yet durable responses remain elusive in 6070% of patients due to clonal heterogeneity and adaptive resistance mechanisms [8,9,10,11,12]

Chemosphere 204 , 156162 (2018)

Immune Function : Supports a healthy immune system

Now Im not talking below average B12, or suboptimal B12 levels, or even whats clinically called B12 depletion, where your levels place you at high risk for deficiencybut actual bonafide vitamin deficiency, meaning that your levels are so low your biochemistry is screwed up