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JAMA 305 , 16591668 (2011)

Hospital, Taipei, Taiwan Objective : Detecting vertebral fractures (VFs) is crucial for effective secondary fracture prevention, as they are linked to higher risks of future fractures

Furthermore, radioresistance and damage to normal brain tissue from radiotherapy, coupled with chemotherapy limitations including poor blood-brain barrier (BBB) penetration, drug resistance, and significant side effects, collectively reduce overall treatment efficacy [7]