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11 , e1004477 (2015)

CB-839 was a gift from Calithera

Reporting summary Further information on research design is available in the Nature Portfolio Reporting Summary linked to this article

The mice were raised in standard environment with a temperature of 23-25 C and a 12-hour light-dark cycle and provided food and water ad libitum

Responsible information tends to be modest and specific

C-reactive protein (CRP), an active regulator of host innate immunity, is a biomarker of severe COVID-19 disease, including lung and atherosclerotic disease progression