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doi: 10.1186/1743-1050-2-13 7 DambalaK.VavilisD.BiliE.GoulisD

doi: 10.1371/journal.pone.0022552 13 MaiaALKimBWHuangSAHarneyJWLarsenPR

If the antibody construct is produced intracellularly, as a first step, the particulate debris, either host cells or lysed fragments, are removed, for example, by centrifugation or ultrafiltration

Intravenous injection of BTZ in rats was found to inhibit proteasome activity in the blood, sciatic nerve, and DRG, while the brain remained unaffected (Meregalli et al., 2014)

Patients underwent comprehensive ophthalmic evaluations at baseline, 3 months, and 6 months, including Humphrey perimetry, PERG recordings, and RNFL thickness measurement using OCT