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Oxidative stress is thought to be an important underlying factor in DS-related pathologies

2) Improves skin tone in both exposed & covered body parts

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Biotime, Shanghai, China), apoptosis inhibitors Z-VAD-FMK (BioVision, California, USA), Z-ATAD-FMK (BioVision, California, USA), and NS3694 (Calbiochem, Billerica, MA, USA), at 2 h before the addition of H 2 O 2 and/or TGF-1

To expand this therapeutic space, our previous work utilized an integrative computational design and experimental screening approach to identify novel Cn-NFAT inhibitors derived from alternative substrates