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Moreover, whether combined inhibitors/inducers of ferroptosis and inhibitors/agonists of biomolecular methylation can function synergistically to mitigate related diseases needs to be explored in depth

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Given that the risk factors for all-cause mortality among the four poor outcomes were relatively well established, to verify the methodological error of the Cox analysis for the results in Table 4 results, we performed univariable and multivariable Cox proportional hazards analyses including traditional, AAV-specific, and inflammation-related risk factors along with GPX-3 concentration at diagnosis for all-cause mortality during follow-up (Supplementary Table S1)