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Gene 247:255264 Panagiotidis CA, Blackburn S, Low KB, Canellakis ES (1987) Biosynthesis of polyamines in ornithine decarboxylase, arginine decarboxylase, and agmatine ureohydrolase deletion mutants of Escherichia coli strain K-12

SOD2 plays a dichotomous role as a tumor suppressor enzyme in the early stages of tumorigenesis while simultaneously acting as a tumor promoter in the process of metastasis

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13 Complicating this further, excessive insulin levelsanother prominent feature of a high percentage of cases of PCOSalso contribute to hyperandrogenism

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