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The cryo-EM maps and coordinates for the GluK2 in the shallow-desensitized state have been deposited in the EMDB under accession numbers EMD-48762 (ATD), EMD-48763 (LBD-TMD), and EMD-48761 (full-length, consensus map), and in the PDB under accession codes 9MZN (ATD), 9MZO (LBD-TMD), and 9MZM (full-length) respectively

Standard RDA: 2.4 mcg for adults Senior-Specific Needs: Often higher than 2.4 mcg due to absorption issues Recommended Intake for Seniors: At least 2.4 mcg, potentially much higher with supplementation Why the Standard 2.4 mcg May Not Be Sufficient The standard 2.4 mcg dosage might not be enough for seniors for a few reasons: Decreased Stomach Acid: Needed for B12 release from food Atrophic Gastritis: A common condition in older adults that makes it hard to absorb B12 Medication Interference: Some medicines can also block B12 absorption For those over 50, its best to get most of their vitamin B12 from supplements and fortified foods

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