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The osteogenic-ARKO and SARM literature studying skeletal morphology has classically used the distal femur and lumbar vertebrae because of their load-bearing potential with high trabecular bone content properties [224], which make these tissues dynamic and highly involved in tissue remodeling via bone resorption and formation

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For patients with PD-L1- a/m TNBC disease, upcoming phase III trials to determine the optimal first-line therapy include the ASCENT-03 (NCT05382299) trial, which is investigating SG compared to treatment of physicians choice and TROPION-Breast 02 (NCT05374512), which investigates Dato-DXd against treatment of physicians choice

And a lot of practitioners, I feel they see that it can really help their patients with Hashimotos