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For example, TNF-, IL-1, IL-6, IL-8 and IL-17A can stimulate inflammatory reactions in arthritic joints and synovial tissues (158, 188, 190), and play an important role in the development of RA

Extended data Extended Data Fig

Three patients with BRIC-1 had compound heterozygous variant in the ATP8B1 gene and 1 had heterozygous while 2 patients with BRIC-2 had compound heterozygous in the ABCB11 gene and 1 had heterozygous

Cellular anti-inflammatory efficiency The progression of rheumatoid arthritis is related with various biochemical cues especially oxidative stress 4

The generation of hydroxyl radicals and the subsequent Fenton reaction are pivotal to the bactericidal efficacy of these antibiotics (Kohanski et al., 2007)

Vitamin C : Renowned for its brightening and anti-aging properties, Vitamin C boosts collagen synthesis, improves skin elasticity, and enhances overall skin glow