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The p K a calculation was carried out with the equilibrated protein (described above) and any water molecule further than 5 from the protein was removed to diminish the calculation time

TBK1 Mediates ICOS Signaling for T FH Maturation and GC-Mediated Antibody Responses Similar to other CD4 + T cell subsets (Th1, Th2, Th17, and Treg cells), T FH development is a multi-step process which involves initial priming of nave CD4 + T cells by dendritic cells in the T cell zone, followed by expansion and differentiation that are regulated through signaling pathways activated downstream of cytokines and cell surface molecules

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n = 3) or the soma volume of microglia in response to dysbiosis (Fig