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Clinically, elevated PLSCR1 expression correlates with reduced sensitivity to neoadjuvant chemotherapy and poorer prognosis in TNBC patients

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This observation is consistent with the DRB1*15:01 allele belonging to one of the three oldest ancestral haplotypes (DR2-DQ6, DR3-DQ2, and DR4-DQ8), which have survived over time due to their ability to recognize a greater diversity of antigens, allowing them to detect and eliminate a greater number of pathogens (113, 114)

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Healthy antioxidant activity is important for maintaining cellular wellness, supporting healthy aging, and promoting overall vitality as part of a balanced lifestyle

Environ Health Perspect 113:15551560 Meacher DM, Menzel DB (1999) Glutathione depletion in lung cells by low-molecular-weight aldehydes