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Kircheis G, Nilius R, Held C, Berndt H, Buchner M, Gortelmeyer R, et al

Works as an anti-ageing compound

Following the above general procedure E, the reaction was purified by flash-column chromatography on silica gel to provide the desired ethyl 4-(adamantylamino)-3-(pyrimidin-5-ylmethyleneamino)benzoate (SRS15-72, Scheme 3) (99 mg, 0.245 mmol, 77%)

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It also inhibits lysosomal and endosomal degradation pathways, preventing autophagic clearance of misfolded proteins and damaged organelles