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10.7150/ijbs.33837 18 ChiX.ZhangR.ShenN.JinY.AlinaA.YangS.et al (2015)

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Here we demonstrate that two deubiquitinating enzymes (DUBs), Ubp2 and Ubp3, play key roles in editing and recycling polyubiquitin chains on yeast uS10, thereby contributing to the promotion of RQC activity

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Furthermore, by reducing CCO activity and compromising oxidative phosphorylation, copper deficiency compels cardiomyocytes to rely more heavily on anaerobic glycolysis, thereby reinforcing the metabolic shift that underpins pathological reprogramming [104]