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10.1046/j.1469-7580.1999.19430335.x J

J Biol Chem 277, 2694426949

Tetrandrine enhances the ubiquitination and degradation of syk through an AhR-c-src-c-Cbl pathway and consequently inhibits osteoclastogenesis and bone destruction in arthritis

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While a number of clinical trials involving Fragment 176-191 have shown that this peptide has a good safety profile, it is currently classified as a research chemical and has no approved medical use