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In this review, the specific effects of natural compounds on OCSCs including blocking the cell cycle, inhibiting tumor growth, reducing tumor migration and invasion, and reversing drug resistance are summarized in detail, which is conducive to giving full play to its multiple bioactive roles in the treatment of ovarian cancer, and provides an important insight into the treatment of ovarian cancer, in the hope of providing new ideas for the treatment of ovarian cancer

Unlike other drug trials, integrative oncology studies encounter additional methodological issues such as the plethora of supplement formulations and their composition, variability in concentration of bioactive compounds across different source materials, patient-driven simultaneous use of products and multifaceted endpoints that include tumour response objective assessments as well as symptom control, quality-of-life evaluation, and biomarker modification (19)

doi: 10.1128/mBio.00220-13 272 MoyesDLWilsonDRichardsonJPMogaveroSTangSXWerneckeJet al

Relation of serum levels of testosterone and dehydroepiandrosterone sulfate to risk of breast cancer in postmenopausal women

Vancomycin may also be given intraperitoneally, which is preferable in bacterial peritonitis cases

15 It is hypothesized that fat embolic and thromboembolic phenomenon following injections exist when gluteal veins are transected, allowing fat macro- or microparticles to be injected intravascularly