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These findings are in accordance with our previous report of mitapivat treatment of -thalassemic (Hbb th3/+ ) mice (39)

Degradation of active ingredients can lead to more severe and less predictable reactions

Vital signs, safety and tolerability were assessed before and 24-26 hours after each dose and 14 3 days after the last dose

These designations ensure the facility maintains clean-room sterility, precise batch verification, and proper cold-chain handling

Levels of tGSH in the TIF were much higher than reported amounts added to formulations of cell culture media (Extended Data Fig

Inhibition or knockdown of ABC transporters enhances susceptibility of adult and juvenile schistosomes to Praziquantel