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Multiple clinical trials have found that GLP-1 receptor agonists particularly semaglutide restored ovulatory cycles in previously anovulatory women with PMOS

R., Johnston, C

doi:10.1016/0006-3223(95)00628-1 PubMed 42

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It is being used in around 35 other countries like China to treat conditions such as chronic hepatitis B and C

These numbers are unprecedented for a non-surgical, pharmacological intervention and notably the weight-loss curve had not fully plateaued at 48 weeks, suggesting that even greater reductions might occur with longer exposure