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However, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) significantly increased in CCPCA i.t

In HD, activation of AMPK mediates neuronal atrophy downstream of oxidative stress [81]

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Meanwhile, the VL is characterized by an over-inflammation or increase of the volume of such organs, including the bazo, the spleen (known as splenomegaly), the liver (hepatomegaly), and lymph nodes (lymphadenopathy) (Hide et al., 2007